Unlike the other bosses in Curse of Naxxramas, Patchwerk has no cards in his deck. He also does not draw cards each turn. However, he is still subject to fatigue damage if forced to draw cards.
The only card that Patchwerk has is the single weapon that is pre-equipped at the start of the battle.
Kobold Stickyfinger stealing Patchwerk's weapon will nullify all damage he can deal.
The only contingency is that you have to survive until you can draw and play the card - Heroic Patchwerk will kill you long before that point unless the rest of your deck is properly defensive.
With no cards in his hand and no cards in his deck, Jeeves' end of turn effect will cause Patchwerk to rapidly suffer large amounts of Fatigue damage, by making him attempt to draw 3 cards.
Patchwerk is one of Kel'Thuzad’s most powerful abominations—his strength and speed come as a shock to those that may face him in combat. Far from a sluggish, mindless undead, Patchwerk uses his immense power to pulverize any tiny meat thing that may face him with a flurry of potent, powerful attacks. He just wants to play![1]
In World of Warcraft
"Behold, Patchwerk. When word of his existence first reached the ears of the Brotherhood, none believed the tales of an abomination with such immense speed and strength. Fewer still believed it when he fell the first time…"
Patchwerk was originally intended to be a collectible reward from the Curse of Naxxramas adventure. His original design was as a 10 Mana 14/14 minion.[2]
Construct Quarter.
Kobold Stickyfinger stealing Patchwerk's weapon will nullify all damage he can deal.
Mind Vision or 
Madame Lazul
Jeeves' end of turn effect will cause Patchwerk to rapidly suffer large amounts of Fatigue damage, by making him attempt to draw 3 cards.
Kel'Thuzad’s most powerful abominations—his strength and speed come as a shock to those that may face him in combat. Far from a sluggish, mindless undead, Patchwerk uses his immense power to pulverize any tiny meat thing that may face him with a flurry of potent, powerful attacks. He just wants to play![1]
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Patch 1.1.0.6024 (2014-07-22):